In the part of the country I'm from, squirrel hunting is very common. It's also traditional for women to eat cooked squirrel brains in scrambled eggs as delicacy. Squirrel brains are major vector for CJD. It tends to show up 30-50 years after consumption. My great-Aunt by marriage died from CJD as have many women I knew
It seems to be a real crapshoot, something along the lines of squirrel roulette. Women the region continue eat squirrel brains as traditional practice and most never get CJD. My Mom and Grandma tried to force the squirrel brains scramble on me, "But it's full of vitamins." I would wriggle loose and run out the door, safe once again.
Grandpa gave me some sage advice, "Don't eat that crap, boy." Besides we usually cut the heads off with wire cutters, not enough meat to fool with.